3M unveils ‘Harvest RC clarifier’- a single-stage purification solution


American multinational conglomerate company, 3M’s division- 3M Health Care has reportedly introduced 3M™ Harvest RC clarifier, offering its fibrous chromatography media to provide a single-stage purification technology for recombinant protein therapeutic development.

As a next-gen in clarification and harvest solution, the technology creates a viable option to enhance the monoclonal antibody yields along with streamlining a multi-stage harvest clarification procedure into a single platform.

Dr. Alexei Voloshin, Application Development Manager at 3M Separation and Purification Sciences, said that with cell structure procedures becoming intensified to provide higher cell densities, the ability to harvest the cell structure fluid effectively and with consistency is becoming challenging.

Dr. Alexei added that the novel 3M Harvest RC clarifier is an advanced solution that fights these challenges along with removing various stages to enhance the biopharmaceutical purification system.

Elaborating further on the abilities of the latest solution by 3M, the Harvest RC clarifier is capable of supporting single-stage clarification across various cultures with different cell densities, cell structure properties, and high packed cell volumes.

Additionally, the technology allows producers to gain predictable performance without the need to program each step. Moreover, the clarifier is available for discovery through commercial volumes.

Seemingly, the solution also offers high mAb product recovery of more than 95% with an improved upstream harvest and clarification process that compresses three steps into one.  

It is worth mentioning that the 3M Harvest RC clarifier offers chromatographic separation that helps in removing soluble impurities, leading to cleaner effluent.

Other benefits include manufacturing flexibility, high yield, and a reduction in processing stages, hence lowering the total cost of manufacturing.

3M Separation and Purification Sciences Division uses advanced 3M material science that increases the levels of purification, filtration, and segregation to support manufacturing, and provide quality solutions.

Source Credit: https://www.prnewswire.com/in/news-releases/new-3m-tm-harvest-rc-clarifier-brings-chromatography-technology-to-harvest-clarification-with-a-single-stage-solution-for-upstream-processes-818736752.html